Cerebral palsy (CP)

Cerebral Palsy (CP) (also cerebral pares) is an umbrella term encompassing a group of non-progressive, non-contagious motor conditions that cause physical disability in human development.

Cerebral refers to the cerebrum, which is the affected area of the brain (although the disorder most likely involves connections between the cortex and other parts of the brain such as the cerebellum), and palsy refers to disorder of movement. CP is caused by damage to the motor control centers of the developing brain and can occur during pregnancy (about 75 percent), during childbirth (about 5 percent) or after birth (about 15 percent) up to about age three. Further research is needed on adults with CP as the current literature is highly focused on the pediatric patient.

Cerebral palsy describes a group of permanent disorders of the development of movement and posture, causing activity limitation, that are attributed to non-progressive disturbances that occurred in the developing fetal or infant brain. The motor disorders of cerebral palsy are often accompanied by disturbances of sensation, perception, cognition, communication, and behavior, by epilepsy, and by secondary musculoskeletal problems.

There is currently no cure for cerebral palsy and no standard therapy that works for all patients. Many of the brain damage-related incidents that cause cerebral palsy occur during pregnancy, making prevention difficult. This has lead many researchers to believe regenerative stem cell therapies provide an option to regenerate nerve tissue and repair damage to the brain.

Cerebral palsy, which affects about 500,000 people in the United States alone, is defined as brain damage that occurs before or during birth. The number of people with the disorder has increased over the last 30 years as more premature babies survive. Its effects are variable, from barely detectable to devastating loss of motor control. The causes are diverse as well, including everything from oxygen deprivation during birth to prenatal infections.

In-vitro studies have shown cord blood stem cells are able to differentiate into neural cell types. In animal models, research has demonstrated convincing evidence that cord blood stem cells injected intravenously migrate to the brain (passing the blood-brain barrier) and improve neurological function and promote healing. The results from such studies lead many researchers to suggest that infusion of cord blood stem cells could alleviate damage to the brain tissue, reduce muscle spasm and improve gait and mobility-related problems in humans.

Example protocol: Stem cells:

  20,000,000 stem cells

• 2x Stem Cell injections via Lumbar Puncture injection (5,000,000 each injection)
• 2x Stem Cell injections via IV injection (5,000,000 each injection)

4 x stem cell growth factor specific to condition type

Depending on the level of severity of the condition, a treatment plan will be given. This may well entail follow-up treatments as our doctors will give in their view, the program which will potentially give optimum benefit to the patient. The cost of treatment can also vary slightly depending of the number of cells, additional elements to treatment and/or if hospitalization is required.

Example daily stem cell therapy treatment plan for Cerbral Palsy:

Treatment plan:

Day 1:

• Medical check up
• Pathology and blood screening
  

Day 2:

• Stem Cells: via IV injection : 5,000,000 stem cells
• Stem Cell growth factor injection -GCSF

Day 3:

• Stem Cells: via lumbar puncture injection : 5,000,000 stem cells
• Stem Cell growth factor injection -NGF
  

Day 4:

• Clear

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