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Stem Cells

Stem Cell treatment for Liver Cirrhosis

Mr. D. Brown: Advanced stage liver cirrhosis and ascites



Patient: Mr. D. Brown

Gender: Male

Country:  UK

Conditions/reasons for treatment:

Advanced liver cirrhosis and ascites (water retention)

Patient’s expectations of possible improvement after therapy:

Regain some liver function and get rid of water retention

Start Date of therapy program:
29/9/09

Treatment location: Bangkok, Thailand

Treatment program: 8 days

  •  20,000,000 human umbilical cord blood-derived stem cells
               (20,000,000  cd34+ stem cells)

 

  • 3x IV injections of cd34+ umbilical cord blood stem cells
  • 1x Local injection into Liver of cd34+ umbilical cord blood stem cells
  • 7xHigh dose hepatocyte growth factor via IM injection

Day 1:
  • Blood screening and liver function report
  • High dose hepatocyte growth factor via IM injection


Day 2:
  • Stem Cell therapy: 5,000,000 cd34+ stem cells : IV injection
  • High dose hepatocyte growth factor via IM injection

Day 3:
  • High dose hepatocyte growth factor via IM injection

Day 4:
  • Stem Cell therapy: 5,000,000 cd34+ stem cells : IV injection
  • High dose hepatocyte growth factor via IM injection

Day 5:
  • High dose hepatocyte growth factor via IM injection

Day 6:
  • Stem Cell therapy: 5,000,000 cd34+ stem cells : IV injection
  • High dose hepatocyte growth factor via IM injection

Day 7:
  • High dose hepatocyte growth factor via IM injection
Day 6:
  • Stem Cell therapy: 5,000,000 cd34+ stem cells : IV injection
  • Collection of 3 month supply of condition specific oral admin stem cell enhancing nutrition


The patient was treated at our medical centre in Bangkok, Thailand as an outpatient. Their accommodation was luxury serviced apartments directly opposite the medical centre.

 

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Comments and updates on patient over past 2 months:

David was in a very advanced stage of Liver disease, his SGOT level before treatment was sitting at 43 U/L and SGPT was sitting at 27 U/L, his albumin levels were very low, sitting at 2.8 g/dl. His ascites was very far advanced and causing him mobility and breathing problem.


After administration of stem cells his ascities continued to cause him problems and we performed an abdominal tapping procedure to remove around 3 litres of fluid. This came straight back and worsened. David went for a second tapping and this has now not returned.


He is now urinating alot during the day, compared to before treatment, when he recalls maybe once or twice a day.
Second liver function tests show SGOT sitting at 27 U/L and SGPT sitting at 19 U/L, this would suggest if interpreted in a positive manner, a lowering of liver cells being destroyed. Taking into account his increase in urination, ascites not returning and the lowering of enzyme levels indicating liver cells bursting, we should think in a positive manner.

 

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David will undergo a second course of stem cell treatment:

3 months:


Each month
5,000,000 cd34+ stem cells
5,000,000 mesenchymal stem cells
2 x high dose hepatocyte growth factor


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